Discovery of gene candidates related to strabismus onset

October 27(Fri), 2017

The research group led by Associate Professor Toshihiko Matsuo of Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences identified the two genes (MGST2 and WNT2) for the first time in the world as gene candidates related to the onset of strabismus, a type of eye disease. The result of this research was published in the American online science magazine PeerJ on October 17.
Strabismus is a “multifactorial disease” in which both genetic and environmental factors are involved in the onset. Patients with strabismus have misaligned sight in one eye, which makes it difficult to use both eyes well and may cause the loss of the function to see objects three-dimensionally. The result of this research is expected to greatly contribute to ophthalmic medical care in the future.


Article Information

DOI: 10.7717/PeerJ.3935

Authors: Jingjing Zhang and Toshihiko Matsuo

Journal: PeerJ

Title: MGST2 and WNT2 are candidate genes for comitant strabismus susceptibility in Japanese patients.

Year of Publication: 2017


Okayama University Silicon Valley Office (OUSVO)

Contact: Mototaka Senda, Ph.D.

Phone:    (1)510-894-3067


strabismus, MGST2, WNT2

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